Friday April 26, 2024
12:00-1:00pm, Digital Auditorium
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5-Fluorouracil Exerts Cytotoxic Chemotherapy Independently of Oxidative Stress Pathways in Breast Cancer Cells
By Rachel Walker, Evelyn Buehren Faculty Mentor: Dr. Laura Sipe Abstract 5-Fluorouracil Exerts Cytotoxic Chemotherapy Independently of Oxidative Stress Pathways in Breast Cancer Cells Rachel Walker and Evelyn Buehren Faculty Advisor: Dr. Laura Sipe Chemotherapy, the main treatment option for triple-negative breast cancer, targets actively dividing cells resulting in cell death. Many chemotherapies result in…
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A Computational Analysis of the Thermodynamic Synthesis of Ammonia Utilizing Transition State Theory
By Vallarie Burge, Rowan Neall Faculty Mentor: Leanna Giancarlo Abstract The synthesis of ammonia (NH3) is an important step in the production of fertilizers that increase the level of nitrogen in soil, bettering plant structure and metabolism. The kinetics of NH3 synthesis was examined and analyzed utilizing transition state theory (TST) in order to understand…
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An Analysis of The Eastern Oyster and its Impact on Community Biodiversity
By Aidan Shell Faculty Mentor: Bradley Lamphere Abstract An Analysis of The Eastern Oyster and its Impact on Community Biodiversity The Eastern Oyster (Crassostrea virginica) has played a crucial role in the Chesapeake Bay ecosystem since the 19th century. The species offers a range of services for both humans and other aquatic organisms from habitat…
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Analysis of water samples from drinking fountains from various buildings across the University of Mary Washington on the presence of the trace of metals (Fe, Al, Pb, Zn, Cr, Cu, Mn)
By Cameron Hyatt, Marina Klein, Iaroslavna Kovalenko, Timothy McCarthy Faculty Mentor: Sarah Smith Abstract Water plays an essential role in everyday life, and different containments in water can affect human health. The water samples from six water fountains across the University of Mary Washington campus will be compared and analyzed on the presence of metals…
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Assessing the potential interactions between climate change and trace metal toxicity in the embryonic Seminole ramshorn snail (Planorbella duryi)
By Joseph Gasink Faculty Mentor: Tyler Frankel Abstract Based on projected modeling, increases in surface water temperatures due to climate change will pose a host of new challenges for poikilothermic aquatic organisms. Additionally, little is known about how this added stressor will interact with the impacts of known environmental contaminants. As such, this study was…
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Beyond Porites corals – evaluating the geochemistry from large skeletal architectural corals from the central tropical Pacific as reliable archives for climate change
By Jessica Oberlies Faculty Mentor: Pamela Grothe Abstract The central tropical Pacific is a key region for studying climate change because it modulates global climate variability, such as through the El Niño Southern Oscillation (ENSO). However, there is a lack of climate records prior to the mid-1950’s from this region, making it difficult to quantify…
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Changes of TOB in Response to Chronic Social Stress
By Hannah Stottlemyer Faculty Mentor: Dr. O'Dell Abstract We investigated the expression of TOB2 in the hippocampus. Using female mice as models, we socially isolated them to serve as a chronic social stressor. TOB2 has an anti-proliferative effect and negatively regulates a gene expression signaling pathway. After sacrificing the mice, extracting the hippocampus, and isolating…
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Character Essentialism in High Fantasy: A Case Study of Dungeons and Dragons
By Garrett Welch Faculty Mentor: Dr. Jeff McClurken Abstract The topic I studied for the capstone experience is the issue of racial essentialism implicit in many modern high fantasy worlds and systems, with a particular focus on Dungeons and Dragons as a case study. In Dungeons and Dragons, players create a unique character and act…
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Characterization of Bacillus Bacteriophage Jabberwock proteome using protein prediction tools
By Stephen Zdgiebloski and George Wanis Faculty Mentor: Dr. Swati Agrawal Abstract Bacteriophages, commonly referred to as phages, are viruses that target and replicate within bacteria with remarkable specificity towards their specific hosts or related species. They offer a promising alternative for combating antibiotic-resistant bacteria without disrupting the normal microbiome or causing damage to human…
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Comparison Images of Deletion vs. RNAi in C. elegans for use in Genetics Class
By Stephanie L. Bailey Faculty Mentor: Theresa M. Grana Abstract COMPARISON IMAGES OF DELETION VS. RNAi IN C. ELEGANS FOR USE IN GENETICS CLASS. Stephanie L. Bailey & Theresa M. Grana. University of Mary Washington, Biology Department. The UMW General Genetics course labs introduce students to several genetic model organisms, including Drosophila melanogaster (crosses and…
