Tag: Madeline Brunt

  • Knockdown of Pvr and its Relation to DM1 Muscle Wasting in Drosophila

    By Madeline Brunt Faculty Mentor: Dr. Ginny Morriss Abstract Myotonic dystrophy type 1 (DM1) is an inherited multisystem disorder that causes severe muscle wasting. DM1 results from CTG-repeat expansions in the untranslated region of the dystrophia myotonica protein kinase (DMPK) gene. While the cause of DMl is known, the underlying mechanism behind DM1 muscle wasting…