Tag: Delaney Baratka
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Simvastatin Reduces Inflammatory Effects in LPS-Stimulated RAW264.7 Macrophages
By Sana Aftab, Analisa Ayala, Delaney Baratka Faculty Mentor: Laura Sipe Abstract 34.6% adults in the U.S. deal with systemic inflammation. Simvastatin is a drug in the class of statins typically used as a treatment to lower cholesterol. Previous research conducted on simvastatin in relation to inflammation found that simvastatin can have anti-inflammatory effects by…
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The Role of the Pvr Signaling Pathway in Drosophila melanogaster Muscle Phenotypes
By Delaney Baratka Faculty Mentor: Dr. Ginny Morriss Abstract Myotonic Dystrophy Type One, DM1, is a progressive, multisystemic, and autosomal dominant disorder caused by expansion of CTG-repeats in the 3′-UTR of the DMPK gene. While we understand the causal mutation that leads to DM1, the underlying mechanisms of disease progression remain unclear. Prior research in…