Category: Poster Presentation
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Temperature and Sex Determination in TU Line Zebrafish
By Ravi Palat Faculty Mentor: Dr. Dianne Baker Abstract The purpose of this project was to investigate the relationship between water temperature and sex determination in the TU line of a commonly used model organism, the zebrafish (Danio rerio). While wild type zebrafish have a distinct sex determining region in their genome, the two most…
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Synthesis Of Myclobutanil Through Appel Halogenation and Nucleophilic Addition Of Formaldehyde Using 4-Chlorobenzyl Cyanide
By Nelson Bonilla Faculty Mentor: Dr. Davis Oldham Abstract Synthesis Of Myclobutanil Through Appel Halogenation and Nucleophilic Addition Of Formaldehyde Using 4-Chlorobenzyl Cyanide Nelson Bonilla, Dr. Davis Oldham Abstract Myclobutanil (MT) is a chiral Triazole fungicide whose main use in agriculture is the active inhibition of vital fungal enzymes, thereby inhibiting fungal growth in crops.…
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5-Fluorouracil Exerts Cytotoxic Chemotherapy Independently of Oxidative Stress Pathways in Breast Cancer Cells
By Rachel Walker, Evelyn Buehren Faculty Mentor: Dr. Laura Sipe Abstract 5-Fluorouracil Exerts Cytotoxic Chemotherapy Independently of Oxidative Stress Pathways in Breast Cancer Cells Rachel Walker and Evelyn Buehren Faculty Advisor: Dr. Laura Sipe Chemotherapy, the main treatment option for triple-negative breast cancer, targets actively dividing cells resulting in cell death. Many chemotherapies result in…
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The Electric Piano-Guitar
By Donald Glander Faculty Mentor: Rebecca Callaway Abstract Though it may not seem like it at first, a piano (not an electric piano, a true acoustic piano) can be thought of as a string instrument. The keys, pressed by a musician, activate levers which strike a string, producing sound. But pianos are large and clunky,…
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Knockdown of Pvr and its Relation to DM1 Muscle Wasting in Drosophila
By Madeline Brunt Faculty Mentor: Dr. Ginny Morriss Abstract Myotonic dystrophy type 1 (DM1) is an inherited multisystem disorder that causes severe muscle wasting. DM1 results from CTG-repeat expansions in the untranslated region of the dystrophia myotonica protein kinase (DMPK) gene. While the cause of DMl is known, the underlying mechanism behind DM1 muscle wasting…
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Fluid Dynamics and Constructing a Flume
By Boone Fleenor Faculty Mentor: Desmond Villalba Abstract Fluid dynamics is a physics discipline that describes the way fluids move and interact between themselves as well as their environment. To fabricate interactions and study the consequences, a controlled and isolated environment is required. A flume is an example of a controlled environment because it isolates…
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Methionine Restriction Decreases Cell Proliferation And aensitizes to chemotherapy
By Loren Delgadillo Llano, Briza Valdes-Llamas, Wagma Zaki Faculty Mentor: Laura Sipe Abstract Triple negative breast cancer (TNBC) is an aggressive subtype that is difficult to treat, resulting in a 66% 5-year survival rate for regional invasion to nearby structures or lymph nodes. This creates an importance to researching the various chemotherapy efficacy methods on…
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Effect of Lithium Chloride Against NDV in BHK-21 Cells
By Aisling Berrios Faculty Mentor: Lynn Lewis Abstract Newcastle disease virus (NDV) is a severe and fatal disease to poultry, causing widespread economic losses for both industries and private farms. With the search for treatment continuing, this research project aims to uncover the antiviral properties of the antipsychotic drug, lithium chloride, for treatment against NDV…
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Drug Development Targeting KasA in M. tuberculosis
By Megan Baxter Faculty Mentor: Davis Oldham Abstract Tuberculosis is a highly infectious disease affecting the lungs and respiratory system caused by Mycobacterium tuberculosis (M. tuberculosis). As one of the most dangerous lung diseases, recent studies have found existing treatments to become resistant and call for new treatments. Research involving the inhibition of KasA (β-ketoacyl…
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Wildlife Use of Restored and Unrestored Shorelines in Belle Isle State Park
By Elle Toia, Eren Edwards Faculty Mentor: Dr. Andrew Dolby Abstract This research project, conducted from March 12, 2024, to April 21, 2024, aimed to investigate how wildlife utilize restored and unrestored shorelines at Belle Isle State Park. Eastern Virginia’s rivers face a significant erosion problem, leading to the installation of living shorelines as a…
